Analytical Technologies Singapore

microscope

NanoRaman Set up with Bioptentiostat for Tip Enhanced Raman Spectroscopy (TERS) Application

The NanoRaman system equipped with LabRAM Evolution being installed locally by Analytical Technologies’ in-house team.

LabRAM Evolution, the world renowned Raman solution for research and analysis. The integral flexibility of the LabRAM HR Evolution makes it the ideal platform for combined with the fully integral nano-Raman for research to TERS (tip enhanced Raman scattering).  

TERS Tip
Raman Microscope

A close up of the integration of a customised environmental chamber and electrochemical cell within a NanoRaman (as shown above) setup designed a sophisticated and versatile experimental configuration to enhance the capabilities of this analytical instrument.

This integrated system is further augmented by the inclusion of a bipotentiostat, a critical component for conducting Tip Enhanced Raman Spectroscopy (TERS) experiments.  

Personalised hands-on guidance and training provided by a HORIBA’s application scientist represents a valuable and tailored educational experience designed to empower researchers, technicians, and users with the skills and knowledge required to make the most effective use of HORIBA’s instruments. 

Another angle of the HORIBA’s LabRAM HR Evolution Setup before the integration of NanoRaman, with HORIBA’s in-house software installed in the computer (right). 

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Installation of LabRAM Evolution Confocal MicroRAMAN System

Our local technical support team has successfully commissioned a semiconductor variant of the world renowned LabRAM Evolution Confocal MicroRaman System.  Fully equipped with multiple lasers from UV to NIR and  unique upgrades, the system is able to handle Raman as well as Photoluminescence measurements.

The LabRAM Confocal MicroRaman system microscopes are ideally suited for both micro and macro measurements, and offer advanced confocal imaging capabilities in 2D and 3D. The true confocal Raman microscope enables the most detailed images and analyses to be obtained with speed and confidence.  It is widely used for standard Raman analysis such as PhotoLuminescence (PL), it can also be further integrated for other hybrid analysis.

The system was enclosed using a customised laser safety curtain that was customised & designed by our engineers. The implementation of a custom laser safety curtain around the system is a critical safety measure that protects the well-being of lab personnel. 

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Cryomicroscopy: The coolest technique in pharma research

In the last two decades, cryomicroscopy methods have become widespread and effective tools used by life scientists, pharmaceutical researchers, and more, to examine biological structures close to their native state.1 The capabilities of cryomicroscopy to visualize the structure of biological molecules, such as proteins and protein complexes, make a valuable addition to existing methods such as X-ray crystallography and nuclear magnetic resonance (NMR). Determining the structure of proteins and protein complexes, which are of particular interest as drug targets and are the subject of investigation to gain a deeper understanding of disease mechanisms, is an important element of drug discovery.

在过去的二十年中,冷冻显微镜方法已经成为生命科学家、制药研究人员等广泛使用的有效工具,用于检查接近其原生状态的生物结构1。冷冻显微镜能够可视化蛋白质和蛋白质复合物等物质的生物分子结构,是对现有的方法如x射线晶体学和核磁共振(NMR)等的有价值的补充。确定蛋白质和蛋白质复合物的结构是药物发现的一个重要部分,这对研究药物靶点非常有意义,也是深入了解疾病机制的重要课题,。

Credits: LINKAM – Instrument.com.cn/bio-equip.com

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*New Product* LabRAM Soleil

One of our long-time partner, HORIBA has announced their latest microscope LabRAM Soleil.

LabRAM Soleil is part of one of Horiba’s most famous Raman series; LabRAM spectroscopy. LabRAM spectroscopy is a complete system that provides ultrafast imaging, advanced automation features, intuitive software and a robust design to supercharge researchers’ analyses.

Click below to download brochure, contact us for more information. 

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Beckman Coulter Vi-CELL™ XR Cascade Microtech Microprobe Micromanipulator Coaxial Probe Holder Our dedicated team excels in sourcing consumables tailored to

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Standard Microscope Spectroscopy [HORIBA]

HORIBA is proud to introduce  the new Standard Microscope Spectroscopy (SMS) systems.  The SMS system is a turnkey system that allows microscope to multi-task by performing spectroscopy. With its unique set of accessories, the SMS system is designed to be extremely flexible as it is capable of turning any existing microscopes into a spectrometer. 

​The concept driving these systems is the ability to either leverage an existing standard microscope, or create a fully turnkey system that performs the microscopy function, and adds one or more spectroscopies as a complementary technique.  Multitask your microscope™ is the theme behind these Standard Microscope Spectroscopy (SMS) systems.

Features

  • Capable of performing a wide variety of spectroscopic techniques
    • Raman
    • Steady state & time-resolved Photoluminescence (PL)
    • Reflectance/Transmittance
    • Electroluminescence
    • Photocurrent
    • Dark Field Scattering
  • Highly compatible with any existing standard microscopes
    • Without compromising the imaging functionality

E-Brochure Catalogue

  • Raman
  • Steady state & time-resolved
  • Photoluminescence (PL)
  • Reflectance/Transmittance
  • Electroluminescence
  • Photocurrent
  • Dark Field Scattering

To know more about the SMS system, please request an e-brochure from us

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