Copley’s comprehensive range of world leading products for inhaler testing extends to equipment, software and services for every stage of development for both innovator and generic products.
The devices used for inhaled and nasal drug delivery are collectively referred to as orally inhaled and nasal drug products (OINDPs). Contact us for more information of the products.
The DDU is the total mass of drug emitted from the inhaler and hence available to the patient.Delivered Dose Uniformity (DDU) is measured by firing the test device into a sampling apparatus which contains a filter. The active drug caught on the filter is then dissolved in solvent and analysed using High Pressure Liquid Chromatography (HPLC).
The Aerodynamic Particle Size Distribution (ASPD), along with Delivered dose, is widely recognised as a Critical Quality Attribute in the in vitro characterisation of OINDPs. The ASPD of an aerosol will determine where the particles in that cloud are going to deposit in the body, amongst other information.