Analytical Technologies Singapore

Cryomicroscopy: The coolest technique in pharma research

In the last two decades, cryomicroscopy methods have become widespread and effective tools used by life scientists, pharmaceutical researchers, and more, to examine biological structures close to their native state.1 The capabilities of cryomicroscopy to visualize the structure of biological molecules, such as proteins and protein complexes, make a valuable addition to existing methods such as X-ray crystallography and nuclear magnetic resonance (NMR). Determining the structure of proteins and protein complexes, which are of particular interest as drug targets and are the subject of investigation to gain a deeper understanding of disease mechanisms, is an important element of drug discovery.


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